Coronary artery disease

Coronary artery disease is a leading cause of death in Australia, associated with several other cardiac conditions including heart attack and angina. The impact of coronary artery disease may be mitigated through lifestyle changes, medication, or specialist interventions such as coronary angioplasty.

Coronary artery disease

What is coronary artery disease?

Also known as coronary heart disease, coronary artery disease involves a blockage or narrowing of the coronary arteries that carry blood to your heart muscle. Like every other muscle in your body, the heart muscle requires an adequate supply of oxygen-rich blood to remain healthy and functional.

The narrowed arteries found in coronary artery disease develop due to an accumulation of plaque, which consists of cholesterol, inflammatory cells, calcium, and other waste substances. This results in the artery walls losing their elasticity while also narrowing the space inside, a process known as atherosclerosis. 

Coronary artery disease is a contributing factor to other heart problems such as angina, heart attack, heart failure, and arrhythmia.

What are the risk factors for coronary artery disease?

Many different factors can increase your risk of coronary artery disease, including lifestyle factors, genetic and other non-modifiable factors, and co-existing medical conditions.

Lifestyle risk factors 

Lifestyle factors for coronary artery disease are those with the greatest potential to manage and  reduce your risk of developing atherosclerosis. They include:

  • Smoking, which can accelerate plaque accumulation 
  • A poor diet high in processed foods, fats, sugar, and salt
  • Low levels of physical activity, which contributes to stiffening of the artery walls, plaque development, and poor metabolic health
  • Excessive alcohol intake, which interferes with metabolism and accelerates atherosclerosis
  • Obesity/being overweight, a risk factor for many cardiovascular diseases

Other medical conditions 

Other medical conditions may contribute directly to an increased risk for coronary artery disease through driving plaque build-up and atherosclerosis of the blood vessels. Managing these conditions well improves your symptoms from the condition itself plus has the added benefit of reducing your coronary artery disease risk.

  • Hypertension (high blood pressure)
  • Hypercholesterolaemia (high cholesterol)
  • Diabetes
  • Chronic kidney disease
  • Depression and other mental illnesses
  • Obstructive sleep apnoea

Non-modifiable risk factors

Some demographics or genetic factors may increase your risk of coronary artery disease. Though these factors cannot be removed or reduced, you can still address your coronary artery disease risk in other ways, such as focusing on modifiable risk factors, reviewing with your cardiologist regularly, or undertaking preventative interventions if necessary. 

Non-modifiable risk factors include:

  • Family history of coronary artery disease
  • Older age
  • Male gender
  • Post-menopause for women
  • South Asian or Aboriginal and Torres Strait Islander ethnic heritages

What are the symptoms of coronary artery disease?

It is possible to have early disease without any coronary artery disease symptoms, or even advanced disease, as the condition progresses slowly and even extensive disease can be asymptomatic. This is why understanding your risk factors and seeing a doctor for a cardiac risk assessment are important, particularly if you are aged 45 or older, or 35 and older and living with diabetes.  

The most common symptom of coronary artery disease is chest pain, known as angina.

For some, coronary artery disease only becomes apparent at the time of a heart attack. Symptoms of a heart attack include angina, light-headedness, nausea, arm or shoulder pain, and shortness of breath. This is an emergency and requires immediate medical attention by calling Triple Zero (000).

How is coronary artery disease treated?

Coronary artery disease is often diagnosed only after a heart attack or episode of angina. However, it can be detected early through routine heart health screening or cardiac risk assessment, and managed before coronary artery disease symptoms develop. 

In diagnosing coronary artery disease, your family history, lifestyle, and other known risk factors will guide your doctor’s tests. These may include:

Coronary artery disease treatment requires a personalised plan, taking into consideration your risk factors, test results, and the current state of your coronary arteries. Often, the most effective approach is a combination of treatment strategies.

Lifestyle modifications

If you are a smoker, quitting cigarettes is the single most significant step you can take to reduce your overall cardiovascular disease risk, not just for coronary artery disease. You may also slow or stop the progression of atherosclerosis through a balanced diet lower in saturated fats and salt, regular physical activity, reducing alcohol intake, and taking steps to keep your body weight within a healthy range.

Medication

Alongside healthy lifestyle changes, medications may be needed to help manage co-existing medical conditions that are contributing to your coronary artery disease and heart attack risk. These may be medications to treat hypertension, high cholesterol, or diabetes. Certain drugs can also be prescribed to reduce blood clotting risk or alleviate angina symptoms.

Specialist interventions

Percutaneous coronary intervention (PCI) is a procedure performed by an interventional cardiologist to widen a narrowed coronary artery and restore proper blood flow with the use of a stent. 

Coronary artery bypass graft (CABG) surgery creates an alternative route for blood flow to the heart by grafting a small section of a blood vessel taken from elsewhere around the blockage. CABG surgery is performed by a cardiothoracic surgeon.

Frequently Asked Questions

Yes, in some cases, the atherosclerosis associated with coronary artery disease can partially regress, although it is more common for treatment to stabilise the condition and prevent it from progressing further. There is some evidence that soft (non-calcified) plaque may shrink or regress with medical treatment. 

Coronary artery disease is often silent until angina develops or your first heart attack. You may suspect you have coronary artery disease if you experience chest pain during physical exertion, which may feel similar to indigestion. Even if you do not have any symptoms, it is recommended to have regular heart health checks with your GP or cardiologist if you are over the age of 45, or over the age of 35 and living with diabetes, or over the age of 30 and identify as a First Nations person. Screening tests can diagnose coronary artery disease even in the early stages, allowing your doctor to plan preventative treatment strategies.

No, coronary artery disease and heart attack (also known as myocardial infarction) are two different conditions, though are closely linked. Most heart attacks are complications of coronary artery disease. Coronary artery disease arises from plaque accumulation and stiffening in the walls of the coronary arteries supplying the heart, reducing blood flow to the heart muscle. A heart attack occurs when a coronary artery becomes completely blocked, often due to an inflamed and ruptured plaque from coronary artery disease.

Coronary artery disease treatment in Sydney

At Harbourside Cardiology, our team is dedicated to providing holistic, patient-centred care that aligns with the most recent clinical guidelines and research. We are with you every step of your health journey, providing continuity of care of all heart conditions from initial assessment through to treatment and recovery.

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